FDA Approved
Treatable Diseases with Umbilical Cord Blood
- Stem cells from a newborn’s umbilical cord blood are FDA approved to treat over 80 diseases, helping regenerate the body after chemotherapy, radiation, and other aggressive medical procedures.
- While that’s a compelling reason to bank cord blood, it is important to understand what these treatments are and how stem cells from your child’s umbilical cord blood can help with recovery.
- One of the first things to understand is the difference between treatments where your child uses their own cord blood (autologous) and treatments using your child’s cord blood to treat other family members (allogeneic). There are many diseases that can be treated with autologous cord blood as shown in the table below.
Childhood Cancers - Solid Tumors
- Neuroblastoma
- Retinoblastoma
- Medulloblastoma
Leukemias
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myelogenous Leukemia (AML)
- Acute Biphenotypic Leukemia
- Acute Undifferentiated Leukemia
Lymphomas
- Hodgkin’s Lymphoma
- Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma)
Chronic Leukemia
- Chronic Myelogenous Leukemia (CML)
- Juvenile Chronic Myelogenous Leukemia (JCML)
- Juvenile Myelomonocytic Leukemia (JMML)
- Chronic Lymphocytic Leukemia (CLL)
Myelodyplastic Syndromes (Pre-Leukemia)
- Refractory Anemia
- Refractory Anemia with Ringed Sideroblasts
- Refractory Anemia with Excess Blasts
- Refractory Anemia with Excess Blasts in Transformation
- Chronic Myelomonocytic Leukemia (CMML)
Other Disorders of Blood Cell Proliferation
Anemias
- Aplastic Anemia
- Congenital Dyserythropoietic Anemia
- Fanconi Anemia
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
Inherited Red Cell (Erythrocyte) Abnormalities
- Beta Thalassemia Major (also known as Cooley’s Anemia)
- Diamond-Blackfan Anemia
- Pure Red Cell Aplasia
- Sickle Cell Disease
Inherited Platelet Anomalies
- Amegakaryocytosis / Congenital Thrombocytopenia
- Glanzmann Thrombasthenia
Inherited Immune System Disorders: Severe Combined Immunodeficiency (SCID)
- SCID with Adenosine Deaminase Deficiency(ADA-SCID)
- SCID which is X-linked
- SCID with absence of T & B Cells
- SCID with absence of T Cells, Normal B Cells
- Omenn Syndrome
Inherited Immune System Disorders: Neutropenias
- Infantile Genetic Agranulocytosis (Kostmann Syndrome)
- Myelokathexis
Inherited Immune System Disorders–Other
- Ataxia-Telangiectasia
- Bare Lymphocyte Syndrome
- Common Variable Immunodeficiency
- DiGeorge Syndrome
- Leukocyte Adhesion Deficiency
- Lymphoproliferative Disorders
- Lymphoproliferative Disorder, X-linked (also known as Epstein-Barr Virus Susceptibility)
- Wiskott-Aldrich Syndrome
Myeloproliferative Disorders
- Acute Myelofibrosis
- Agnogenic Myeloid Metaplasia (Myelofibrosis)
- Polycythemia Vera
- Essential Thrombocythemia
Phagocyte Disorders
- Chediak-Higashi Syndrome
- Chronic Granulomatous Disease
- Neutrophil Actin Deficiency
- Reticular Dysgenesis
Cancers in the Bone Marrow
- Multiple Myeloma
- Primary Plasma Cell Leukemia (PCL)
- Secondary Plasma Cell Leukemia PCL)
- Waldenstrom’s Macroglobulinemia
Inherited Disorders Affecting the Immune System and Other Organs
- Cartilage-Hair Hypoplasia
- Gunther’s Disease (Erythropoietic Porphyria)
- Hermansky-Pudlak Syndrome
- Pearson’s Syndrome
- Shwachman-Diamond Syndrome
- Systemic Mastocytosis
Inherited Metaboloc Disorders
Mucopolysaccharidosis (MPS) Storage Diseases
- Hurler Syndrome (MPS-IH)
- Scheie Syndrome (MPS-IS)
- Hunter Syndrome (MPS-II)
- Sanfilipp Syndrome (MPS-III)
- Morqui Syndrome (MPS-IV)
- Maroteaux-Lamy Syndrome (MPS-VI)
Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
- Mucolipidosis II (I-cell Disease)
Leukodystrophy Disorders
- Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN)
- Krabbe Disease (Globoid Cell Leukodystrophy)
- Metachromatic Leukodystrophy
- Pelizaeus-Merzbacher Disease
Lysosomal Storage Diseases
- Niemann-Pick Disease
- Sandhoff Disease
- Wolman Disease
Inherited Disorders–Other
- Lesch-Nyhan Syndrome
- Osteopetrosis